For the indecisive gourmand, Manolo Caracol (Avenida Central and Calle 3, +507 228 4640) serves a set nine-course tasting menu for $36 per person. Busy and smart, yet relaxed, the open kitchen churns out seafood, meat and vegetable dishes made with local ingredients, the majority of which come straight from chef Caracol's farm. Highlights include seafood bisque, corn tortilla with chorizo, and coconut fish curry with yuca tortillas.
Not exactly luxury but tasty and cheap all the same, Mercado del Marisco seafood market (Avenida Balboa and Calle Eloy Alfaro) is a great place to wander. When Anthony Bourdain came to Panama, this was his first stop. Here you'll find rows of al fresco stalls selling ceviche for $1.25 a cup. There's also an upstairs restaurant with a larger menu with hearty fish stews and filleted sea bass.
New Casco Viejo coffeehouse Bajareque sells the world's most expensive coffee, Geisha, for a reasonable $6.50 a cup. Panama is the world's only producer of this rare coffee, which typically retails for $172.50 per kilo. Fitting for its name, Geisha coffee mainly sells in Japan and costs $50 a cup at Tokyo coffee shops like Horiguchi Coffee.
The primary nightlife spots are Calle Uruguay and Casco Viejo, both of which are lined with places to sample Panama's four national beers, Panama, Balboa, Suarana and Atlas, for a couple of dollars.
In Casco Viejo, Habana Panama (Calle Eloy Alfaro y Calle 12 Este; +507 212 0152), isn't just the hottest dance spot in the city, it's an atmospheric salsa hall that recalls the elegance of old Cuba and Ricky Ricardo style. Live bands typically don't hit the stage until midnight. For a typical $10 cover you'll find fewer better shows (or more fun) anywhere.
Then there's Barlovento (Calle 10 A; +507 6613 4345), a tropical-style rooftop bar where the beautifuls hang. With views over Casco Viejo (rather than the Panama City skyline over at Tántalo) and a DJ playing a mix of electronic music and Latin beats, the place is pumping on the weekends. Again there's a $10 cover charge (if you're male that is; women enter free) but you'd easily pay a $25 cover for the same deal in Mexico City.
The oldest section of the city, Panama Viejo was burned to the ground in the late 17th century by British pirate (or privateer, depending who you ask) Sir Henry Morgan.
The crumbling remains of towers, forts and houses run along the coast waiting to be explored. The visitors center has a model showing the city before Morgan showed up.
Panama Viejo; +507 226 8915; $3 for museum, $4 for ruins, $6 for both; open Tuesday-Sunday, 9 a.m.-5 p.m.
The Panama Canal took 250,000 people more than 10 years to build (not counting the original failed French-led effort), transports 40 boats each day (taking eight to 10 hours per transit) and costs an average of $85,000 per vessel.
Luckily, tours are a little less, and a partial transit with Canal & Bay Tours costs $135 per person, including breakfast, lunch and transfer though two sets of locks.
The Panama Canal celebrates its centenary in 2014, and to mark the occasion it's undergoing a $5.25 billion modernization and expansion.
Progress is best viewed from above. Air Charter Panama arranges one-hour helicopter tours covering the Pacific and Atlantic sides of the canal from $749 for three passengers in a Robinson R44.