TAMPA, Fla. -- Backup quarterback Nick Foles had another big game against the Tampa Bay Buccaneers, leading the Philadelphia Eagles to a 31-20 win on Sunday at Raymond James Stadium.
With Michael Vick sidelined because of a hamstring injury, Foles made his seventh career start, going 22-for-31 for 296 yards and three touchdowns and running for a score.
Foles helped seal the game with a 36-yard touchdown strike to DeSean Jackson that put Philadelphia up eight points with under 10 minutes left.
Foles' only two career wins have come against Tampa Bay, having thrown for a career-high 381 yards in a 23-21 victory in Tampa on Dec. 9, 2012.
The Buccaneerss (0-6) received a strong outing by rookie quarterback Mike Glennon but were unable to get their first win of the season.
It took Philadelphia (3-3) just over three minutes to score on their opening drive, with Foles going 4-for-5 for 70 yards before scrambling for a 4-yard touchdown, making it 7-0.
The Eagles set the tone on their first play with running back LeSean McCoy taking a screen pass and racing 45 yards into Tampa Bay territory.
The Buccaneerss appeared to tie the score five minutes into the first quarter when cornerback Darrelle Revis flipped McCoy, forcing a fumble and returning it 39 yards for a touchdown. But after the play was reviewed, Revis was ruled down by contact at the Philadelphia 40-yard line. The Bucs had to settle for a 38-yard field goal by Rian Lindell, cutting the Eagles' lead to 7-3.
Glennon, making his second career start, didn't have one of his top weapons, with receiver Mike Williams sidelined by a hamstring injury. But Glennon was solid, going 26-for-43 for 273 yards with two touchdowns and one interception.
Glennon threw the first of two touchdown passes just over a minute into the second quarter, a 24-yarder to Vincent Jackson that gave the Bucs a 10-7 lead.
But the Eagles answered midway through the second quarter. Jackson beat Revis on a crossing route in the end zone for a 13-yard touchdown to give Philadelphia a 14-10 lead.
The Buccaneerss responded before the half, with Glennon orchestrating an impressive 75-yard drive, including a 16-yard-scramble on a third-and-14, ending with a 2-yard touchdown pass to Jackson.
Glennon threw an interception on the Buccaneers' first drive in the third quarter and the Eagles cashed in. Receiver Riley Cooper caught a 47-yard touchdown pass to put Philadelphia up 21-17 just over three minutes into the quarter.
The Buccaneers inched closer, thanks to a 90-yard drive that started at their 1-yard line and spanned 7:57 between the third and fourth quarters. But Tampa Bay had to settle for a 27-yard field goal by Lindell that cut the Eagles' lead to 21-20.
On the next series, Foles led the Eagles 80 yards in three plays, including Jackson's second touchdown of the game.
NOTES: Williams (hamstring) and G Carl Nicks (MRSA) did not play for the Buccaneers. ... Tampa Bay CB Johnthan Banks, diagnosed with MRSA last week, did play. ... Vick was active but only as an emergency third quarterback. ... Eagles RB Chris Polk suffered a right shoulder injury in the first half and didn't return.